Citrulline CAS 372-75-8 is a type of α- Amino acid, chemical formula C6H13N3O3.

Patients with rheumatoid arthritis (approximately 80%) will develop an immune response against proteins containing citrulline. Although the cause of this reaction mechanism is unknown, detecting antibodies can help diagnose this type of disease.

Chinese name: Citrulline

Foreign name: Citrulline

Nickname: (S) -2-amino-5-urea valerate carbamoyl ornithine

Chemical formula: C6H13N3O3

Molecular weight: 175.19

CAS login number: 372-75-8

EINECS login number: 206-759-6

Melting point: 222 ℃

Water solubility: soluble in water

Density: 1.289 g/cm ³

Appearance: White crystalline

Function

When citrulline is still an amino acid, it is not encoded for DNA, so it is not embedded in proteins in protein biosynthesis. However, some proteins still contain citrulline. These citrullines are produced by peptide arginine aminotransferase (PAD), which converts arginine into citrulline during the process of citrullination. Proteins that generally contain citrulline include human myelin basic protein (MBP), polykeratin microfilament protein, and some histones. Cellulose and vimentin can be aminated from cell death and tissue inflammation.

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