Undecanonylphenylalanine CAS 175357-18-3, also known as acylamine, is a melanogenic hormone（ α- MSH receptor antagonist, acting on α- MSH triggers biochemical reactions in various stages of melanin formation, intercepts melanin generation signals, and controls α- The combination of MSH (melanocyte stimulating hormone) and melanogenesis factor effectively inhibits the activity of tyrosinase, thereby inhibiting the formation of melanin. Mainly used as a whitening agent in cosmetics.

Chinese name: undecanonylphenylalanine

Foreign name: Undecylenoyl Phenylalanine

Nicknames: acylamide, N – (1-oxo-10-undecenyl) – L-phenylalanine, phenylalanine undecenone

Chemical formula: C20H29NO3

Molecular weight: 331.45

CAS login number: 175357-18-3

EINECS login number: N/A

Melting point: 109 to 112 ℃

Boiling point: 540 ℃ (± 50.0 ° C)

Water solubility: easily soluble in esters

Appearance: White powder

Application: Whitening raw materials

Main functions

(1) Acylbenzamide can effectively inhibit α- The formation of melanin caused by MSH can also act on multiple stages of melanin formation, used for whitening or reducing the deposition of melanin on the epidermis, improving skin problems such as dark yellow and rough skin, unifying skin tone, preventing, delaying, and treating excessive pigmentation in the skin (such as excessive pigmentation after inflammation, pigmentation spots such as age spots).

(2) Acylbenzamide can bind to nicotinamide, which can prevent melanin synthesis from the source (i.e., inhibit melanin generation signaling and melanin production enzyme activity), while nicotinamide interferes with the melanin synthesis pathway (i.e., inhibit melanin transport to the stratum corneum and accelerate melanin stratum corneum metabolism), working together to achieve a whitening and spot lightening effect. It can be used to prepare stable lotion, cream, transparent water or gel, etc.

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