Palmitoyl pentapeptide CAS 214047-00-4 is a chemical substance with the molecular formula C39H75N7O10. Labeled as palmitoyl pentapeptide-4 in the 2021 edition of the National Food and Drug Administration’s Catalogue of Used Raw Materials for Cosmetics, also known as palmitoyl pentapeptide-3 before 2006.

Chinese name: Palmitoyl pentapeptide

Foreign name: Palmitoyl Pentapeptide-4; L-Series

Matrix; N2- (1-oxohexadecyl) – L lysyl L threonyl L threonyl L lysyl

CAS: 214047-00-4

Molecular formula: C39H75N7O10

Peptide structure: Pal-KTTKS-OH

Molecular weight: 802.05g/mol

Nicknames: beauty pentapeptide, M-based peptide, N2- (1-oxocetyl) – L-lysine-L-threacyl-L-threacyl-L-lysine-L-serine, pentapeptide, beauty peptide lipopeptide, 5-peptide, M-peptide

Main purpose

Palmitoyl pentapeptide, as one of the first signal peptides applied to skin care products [2], has a clear anti-aging effect, which can effectively improve the skin roughness, reduce the number of fine lines, reduce the depth and area of wrinkles, etc. It is mild and non irritating, and has a lot of basic research and literature to prove its efficacy [3].

1. Palmitoyl pentapeptide-4 can penetrate the dermis and increase collagen, reversing the process of skin aging through reconstruction from the inside out.

2. Palmitoyl pentapeptide-4 is actually a C-terminal fragment of collagen I, which has a similar effect to laser surgery.

3. Stimulate the proliferation of collagen, elastic fibers, and hyaluronic acid, increase skin moisture content and water retention, increase skin thickness, and reduce fine lines.

4. It can increase the absorption effect.

5. 0.01% added to cosmetics

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