Metronidazole CAS 443-48-1 is an organic compound with the chemical formula C6H9N3O3. It is mainly used as an antibiotic and antigenic agent to treat or prevent systemic or local infections caused by anaerobic bacteria, such as those in the abdominal cavity, digestive tract, female reproductive system, lower respiratory tract, skin and soft tissue, bones and joints. It is also effective in treating sepsis, endocarditis, meningeal infections, and colitis caused by the use of antibiotics, The treatment of tetanus is often combined with tetanus antitoxin (TAT) and can also be used for oral anaerobic infections.

Chinese name: metronidazole

Foreign name: Metronidazole; 2- (2-methyl-5-nitroimidazol-1-yl) ethanol

Nicknames: 1- (2-hydroxyethyl) -2-methyl-5-nitrimidazole, 2-methyl-5-nitr-1H-imidazol-1-ethanol, 2- (2-methyl-5-nitrimidazol-1-yl) ethanol

Chemical formula: C6H9N3O3

Molecular weight: 171.154

CAS login number: 443-48-1

EINECS login number: 207-136-1

Melting point: 159 to 161 ℃

Boiling point: 405.4 ℃

Density: 1.45 g/cm ³

Appearance: White to slightly yellow crystalline powder

Flash point: 199 ℃

Physical and chemical properties

Density: 1.45g/cm3

Melting point: 159-161 ℃

Boiling point: 405.4 ℃

Flash point: 199 ℃

Refractive index: 1.612

Steam pressure: 2.67E-07mmHg (25 ℃)

Oil water distribution coefficient: -0.02

Polar molecular surface area: 83.87

Appearance: White crystalline powder

Solubility: Soluble in hot water, slightly soluble in ethanol (5mg/ml, 20 ℃), slightly soluble in water (10mg/ml, 20 ℃) and chloroform, very slightly soluble in ether (less than 0.5mg/ml) [3-4]

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