Omeprazole CAS73590-58-6 is a proton pump inhibitor used to treat diseases such as peptic ulcers and gastroesophageal reflux disease (GERD). It can specifically act on the site where the proton pump is located in gastric parietal cells and convert it into the active form of sulfosamide. It then irreversibly binds to the thiol group of the proton pump through disulfide bonds, forming a complex of sulfosamide and proton pump (H+- K+- ATPase), thereby inhibiting the activity of the enzyme, The final step of blocking gastric acid secretion by preventing the transport of H+within parietal cells to the gastric cavity can significantly reduce the amount of gastric acid in gastric juice. Therefore, this product has a strong and persistent inhibitory effect on gastric acid secretion caused by various reasons, such as basal gastric acid secretion and gastric acid secretion caused by histamine, pentapeptide gastrin, and stimulation of the vagus nerve, including gastric acid secretion caused by dibutylcycloadenosine monophosphate, which cannot be inhibited by H2 receptor blockers. This is related to the irreversibility of the inhibitory effect of this product on the proton pump, and only after the formation of a new proton pump can the acid secretion function be restored.

Specification

Melting point: 156 ° C

Boiling point: 600.0 ± 60.0 ° C

Density: 1.332 g/cm3

Flash point: 9 ℃

Solubility: H2O: 0.5 mg/mL

Appearance: White solid

Application
Used for gastric and duodenal ulcers, stress ulcers, etc.

Used for reflux esophagitis and gastrinoma.

This injection can also be used for: ① gastrointestinal bleeding, such as peptic ulcer bleeding, anastomotic ulcer bleeding, etc., as well as preventing severe diseases (such as cerebral hemorrhage, severe trauma, etc.) and upper gastrointestinal bleeding caused by gastric surgery. ② Acute gastric mucosal injury complicated by stress or caused by non-steroidal anti-inflammatory drugs After general anesthesia or major surgery, as well as in comatose patients, to prevent gastric acid reflux and inhalation pneumonia

When combined with amoxicillin and clarithromycin, or with metronidazole and clarithromycin, it can effectively kill Helicobacter pylori (Hp).

Packing

25kg/drum

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